Genetics of Inflammatory Bowel Disease: which news.
Anna Latiano, Orazio Palmieri
Fondazione IRCCS Casa Sollievo della Sofferenza, Gastroenterology Unit
Notwithstanding the identification of about 240 genetic markers, the disease management of Inflammatory Bowel Disease (IBD) patients has not been modified yet. For patients where IBD is caused by high penetrance genetic variants in a single gene (monogenic IBD), the next-generation sequencing technologies to diagnose monogenic causes are recommend.