CLINICAL SYSTEMATIC REVIEW
Wilson’s disease: certainties and still doubts
Fabiola Di Dato, Raffaele Iorio
Dipartimento di Scienze Mediche Traslazionali, Sezione di Pediatria, Università degli Studi di Napoli Federico II
Wilson’s Disease (WD) is a rare genetic disorder of copper metabolism. Although WD has been known for more than 100 years, due to its rarity, it still has many controversial points from a diagnostic and therapeutic point of view, even more in children than in adults. Here, through a systematic review, we try to answer the main critical issues.