Diagnostic workup and management of VEO IBD
Giulia D’Arcangelo, Marina Aloi
UOC di Gastroenterologia ed Epatologia Pediatrica, Sapienza Università di Roma
Inflammatory bowel disease (IBD) that presents in children <6 years of age is known as very early-onset IBD (VEOIBD). This subgroup of patients is characterized by a more severe and refractory disease course. In around 15-20% of these cases, a specific genetic mutation has been shown giving a distinct phenotype. Targeted gene analysis or wider genetic tests need to be ruled out in these patients.