Recent Advance in Basic Science
Acute and chronic pancreatitis: when some genes play an important role
Floriana Adragna (1), Pasquale Mansueto (1), Claudio Enna (1), Aurelio Seidita (1), Antonio Carroccio (1, 2)
1Dipartimento Biomedico di Medicina interna e specialistica, Università degli Studi di Palermo, Palermo2U.O.C. di Medicina interna, Ospedale Giovanni Paolo II, Sciacca (AG)
Pancreatic inflammatory disease are determined by a set of individual genetic predisposition and environmental triggers. Many genes have been isolated in pancreatic tissues, whose mutation would result in an increased risk of developing pancreatitis. Some of these mutations seem more related to the onset of chronic forms of pancreatitis, others to the onset of acute ones.