News in Pediatric Gastroenterology Pharmacology
Elisabetta Francesca Stacul, Chiara Moretti, Costantino De Giacomo
1S.C. di Pediatria, A.O. Ospedale Niguarda Ca’ Granda di Milano
PPIs are commonly prescribed to infants for managing GERD, however recent literature has demonstrated a lack of efficacy of PPI, specifically in infants with clinical diagnosis of GERD. Regurgitation in infancy needs not be investigated unless there are warning features. PPIs shouldn’t be administered to treat symptoms of GERD in otherwise healthy infant without strong evidence of acid-induced disease.