News in Pediatric Gastroenterology Pharmacology
Sara De Iudicibus (1,2), Giuliana Decorti (2), Stefano Martelossi (1)
1IRCCS Burlo Garofolo di Trieste2Dipartimento di Scienze della Vita, Università degli Studi di Trieste
Glucocorticoids are employed to induce remission in paediatric inflammatory bowel disease, but inter- individual differences in their efficacy and side effects have been reported. Molecular mechanisms involved in variability in glucocorticoid response are still not known, but advance in pharmacogenomics could contribute to the optimization and personalization of therapy.