New insights in the diagnosis and treatment of Cystic Fibrosis liver disease
Angela Sepe, Antonella Tosco, Valeria Raia
Centro Regionale Fibrosi Cistica, Sezione Pediatrica, Dipartimento di Scienze Mediche Traslazionali, Università degli Studi di Napoli Federico II
In Cystic Fibrosis liver disease (CFLD) has a nonunivocal definition, including difficulties in terms of epidemiology, natural history, as well as in the therapeutic choice where UDCA is currently the only available drug. Severe liver disease has a poor prognosis in CF. A better comprehension of safety/efficacy of innovative therapies on CFLD severity is mandatory to identify patients that might show more benefits than risks.