Bifidobacteria and microbiota modulation in allergic prevention
1U.O. di Allergologia – Dipartimento Pediatrico Universitario-Ospedaliero - Ospedale Pediatrico Bambino Gesù
Allergy tends to occur more rarely among members of larger families, where infections occur in childhood. This intuition was called “Hygiene Hypothesis”. With the discovery of the microbiota, this hypothesis was reformulated in the “Microflora hypothesis of allergic disease”. Controversial data have emerged from intestinal microbiota evaluation in food allergy. Bifidobacteria seems to be the most rational solution for allergy prevention. Studies based on the creation of large birth-cohorts will be needed to identify and possibly correct the dysbiosis associated with the appearance of food allergy.