NEWS IN PEDIATRIC GASTROENTEROLOGY PHARMACOLOGY
“Dual Biological Therapy” in Inflammatory Bowel Diseases
Francesca Laganà, Claudio Romano
1Unità Operativa di Gastroenterologia Pediatrica e Fibrosi Cistica Dipartimento di Patologia Umana Dell’Adulto e Dell’Età Evolutiva “G. Barresi” Università degli studi di Messina
The biological therapy has become the therapeutic standard in the management of patients with moderate to severe inflammatory bowel disease (IBD) even in the pediatric age. However, there are still complex patients who do not respond to therapy or who have extra-intestinal manifestations that are not well controlled by therapy. Therefore, the need to try the efficacy of 2 biological drugs with what is called “dual biological therapy” may exist. To date it is not yet approved in clinical practice, but the data reported in the literature on selected patients are promising.