Clinical Systematic Review
Clostridium difficile infection in children
Elena Borali 1, Costantino De Giacomo 2
1 SC di Pediatria, A.O. SS. Antonio e Biagio e Cesare Arrigo, Alessandria 2 SC di Pediatria, ASST Grande Ospedale Metropolitano Niguarda, Milano
Clostridium difficile is a spore-forming, toxinproducing, anaerobic bacillus responsible of a variety of gastrointestinal manifestations raging from asymptomatic carriage to pseudomembranous colitis. Community-acquired Clostridium difficile infection is an increasingly appreciated condition worldwide, involving patient previously considered at low risk such as children and healthy persons.