IBD HIGHLIGHTS
Diagnostic workup and management of VEO IBD
Giulia D’Arcangelo, Marina Aloi
UOC di Gastroenterologia ed Epatologia Pediatrica, Sapienza Università di Roma
Inflammatory bowel disease (IBD) that presents in children <6 years of age is known as very early-onset IBD (VEOIBD). This subgroup of patients is characterized by a more severe and refractory disease course. In around 15-20% of these cases, a specific genetic mutation has been shown giving a distinct phenotype. Targeted gene analysis or wider genetic tests need to be ruled out in these patients.